Prime Highlights:
Olson’s research focuses on understanding how cancer cells spread (metastasize) within the body, aiming to stop this process, which is responsible for most cancer-related deaths.
Olson’s lab is exploring compounds that could block proteins involved in metastasis, with promising results in ovarian cancer models.
Key Background:
Professor Michael Olson, a distinguished academic in the Department of Chemistry and Biology at Toronto Metropolitan University (TMU), has been named the recipient of the prestigious Sarwan Sahota Distinguished Scholar Award for 2025. Olson, a Tier 1 Canada Research Chair in Molecular Cell Biology, is recognized for his pioneering research on cancer metastasis, a critical area of study aimed at preventing the spread of cancer within the body.
Olson’s work diverges from the traditional focus of cancer research, which predominantly aims to eliminate cancer cells. Instead, Olson investigates how cancer cells metastasize, or spread, to other parts of the body—a major cause of cancer-related mortality. By studying the cytoskeleton, a network of proteins responsible for cell shape and movement, Olson has identified key factors that allow cancer cells to become more mobile and invasive, thereby enhancing their ability to spread.
His research has already yielded promising results, including a study in which cancer cells were observed to change shape and become more flexible, enabling them to squeeze through narrow blood vessel walls. Olson’s lab is currently studying compounds that could block these proteins, preventing cancer cells from spreading, with early results in ovarian cancer models showing potential.
Collaboration is at the heart of Olson’s research, as his lab works closely with institutions like the Princess Margaret Cancer Centre and Mount Sinai Hospital. Olson also emphasizes the importance of mentoring, noting the growth of his graduate students, who develop critical thinking skills and become leaders in their own research. Olson will be honored with the Sarwan Sahota Distinguished Scholar Award at the TMU Met Awards Gala, recognizing his significant contribution to cancer research and his impact on both scientific discovery and education.
